SCHEMBL13401924

SCHEMBL13401924

Cc1ccc(COc2ccc(C)c(C)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.59
NPC1 O15118 6/20 0.57
RAB9A P51151 5/20 0.57
MAOA P21397 6/20 0.54
HSP90AA1 P07900 1/20 0.53
HRH3 Q9Y5N1 1/20 0.52
PARP10 Q53GL7 1/20 0.51
ACHE P22303 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12337966 0.94 RAB9A (0.57) MAOBNPC1RAB9AHSP90AA1HRH3
SCHEMBL13929699 0.89 MAOB (0.53) MAOBNPC1RAB9AMAOAHSP90AA1
SCHEMBL17931583 0.88 RAB9A (0.55) MAOBNPC1RAB9AHSP90AA1HRH3
SCHEMBL18636228 0.85 MAOB (0.56) MAOBNPC1RAB9AMAOAPARP10
SCHEMBL8335885 0.85 ALOX5 (0.61) MAOBNPC1RAB9AMAOAHSP90AA1
SCHEMBL26198947 0.84 MAOB (0.55) MAOBNPC1RAB9AMAOAPARP10
SCHEMBL10269942 0.84 HRH3 (0.56) MAOBNPC1RAB9AMAOAHRH3
SCHEMBL17548012 0.84 MRGPRX4 (0.56) MAOBNPC1RAB9AMAOAPARP10
SCHEMBL8930213 0.83 MAOB (0.69) MAOBNPC1RAB9AMAOAHRH3
SCHEMBL891195 0.83 MAOB (0.69) MAOBNPC1RAB9AMAOAHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10343982-B2 Compounds and mesogenic media MERCK PATENT GMBH (DE) 2019-07-09 US disclosed
US-20170210990-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-07-27 US disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343982-B2 Compounds and mesogenic media MTX1, NEFM, MTX2 MAOB 535/4885NPC1 1714/4885RAB9A 836/4885
US-20170210990-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA SP1, FOXM1, S100A11 MAOB 3274/4885NPC1 2140/4885RAB9A 2745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.