Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445687 | 0.90 | PTGS2 (0.50) | PTGS2ELANEALOX15ESR1HIF1A | |
| SCHEMBL13402149 | 0.85 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL13402552 | 0.85 | PTGS2 (0.45) | PTGS2 | |
| SCHEMBL13402243 | 0.84 | PTGS2 (0.43) | PTGS2ELANEALOX15 | |
| SCHEMBL13402185 | 0.82 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL18211363 | 0.81 | ELANE (0.51) | PTGS2ELANEHIF1A | |
| SCHEMBL16326726 | 0.80 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL8039889 | 0.79 | PTGS2 (0.50) | PTGS2ELANE | |
| SCHEMBL8435546 | 0.78 | ALOX15 (0.55) | ELANEALOX15ESR1HIF1AACHE | |
| SCHEMBL13594063 | 0.77 | ALPI (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081786-A1 | Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081786-A1 | Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation | EPOR, LIFR, LNPEP | PTGS2 2438/4885ELANE 783/4885ALOX15 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.