SCHEMBL134056

SCHEMBL134056

Nc1c(S(=O)(=O)O)cc2c3c(cc(S(=O)(=O)O)cc13)C(=O)N(CCNC(=O)CI)C2=O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CLTC Q00610 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ KDM4E B2RXH2 3/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL29531480 0.93 POLB (0.41) CLTCPOLBKDM4EMEN1KMT2A
SCHEMBL12559609 0.87 CLTC (0.49) CLTCPOLBKDM4EMEN1KMT2A
SCHEMBL21404284 0.81 CLTC (0.40) CLTCPOLBMEN1KMT2ACA1
SCHEMBL27404612 0.80 CLTC (0.39) CLTCPOLBMEN1KMT2ACA1
Ethylenediamine SCHEMBL21957845 0.80 CLTC (0.39) CLTCPOLBMEN1KMT2ACA1
SCHEMBL16097930 0.74 ALDH1A1 (0.33) CLTCALDH1A1
SCHEMBL14636508 0.73 CLTC (0.51) CLTCMEN1KMT2ACA1CA2
SCHEMBL8032702 0.73 ALDH1A1 (0.33) CLTCALDH1A1
SCHEMBL7705622 0.72 ALDH1A1 (0.32) CLTCALDH1A1
Lithium SCHEMBL4587867 0.72 ALDH1A1 (0.32) CLTCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458760-B1 ENTRAPPED BINDING PROTEINS AS BIOSENSORS BECTON DICKINSON CO (US) 2012-03-07 — — EP claimed
US-7851593-B2 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY (US) 2010-12-14 — — US claimed
US-20070281368-A1 BINDING PROTEINS AS BIOSENSORS HSIEH HELEN V 2007-12-06 — — US claimed
WO-2005080988-A1 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2005-09-01 — — WO claimed
US-6855556-B2 Binding protein as biosensors BECTON, DICKINSON AND COMPANY (US) 2005-02-15 — — US claimed
US-20050014290-A1 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY 2005-01-20 — — US claimed
US-20230384227-A1 DEVICE AND METHODS FOR QUANTIFYING ANALYTES INTRODUCTION INVITROGEN CORPORATION 2023-11-30 — — US disclosed
US-11635383-B2 Device and methods for quantifying analytes introduction INVITROGEN CORPORATION 2023-04-25 — — US disclosed
US-20210402182-A1 TREATMENT DELIVERY SYSTEM WearOptimo Pty Ltd (AU) 2021-12-30 — — US disclosed
US-20210338158-A1 MEASUREMENT SYSTEM WearOptimo Pty Ltd (AU) 2021-11-04 — — US disclosed
EP-3860453-A1 MEASUREMENT SYSTEM Wearoptimo Pty Ltd (AU) 2021-08-11 — — EP disclosed
EP-3860449-A1 ELECTRODE ARRANGEMENT Wearoptimo Pty Ltd (AU) 2021-08-11 — — EP disclosed
WO-2021062475-A1 ANALYTE MEASUREMENT SYSTEM WearOptimo Pty Ltd (AU) 2021-04-08 — — WO disclosed
WO-2007051112-A2 SERUM PROLACTIN BINDING PROTEIN IN EPITHELIAL CARCINOMA INVITROGEN CORPORATION (US) 2007-05-03 — — WO disclosed
US-20070092920-A1 Serum Prolactin Binding Protein in Epithelial Carcinoma Life Technologies Corporation 2007-04-26 — — US disclosed
WO-2006063213-A2 SERUM AMYLOID A PROTEIN IN INFLAMMATION AND OBESITY UNIVERSITY OF MARYLAND, BALTIMORE (US) 2006-06-15 — — WO disclosed
WO-2006023635-A2 METHODS OF SCREENING PROTEINS BECTON, DICKINSON AND COMPANY (US) 2006-03-02 — — WO disclosed
US-20060040327-A1 Methods of screening proteins AMISS TERRY 2006-02-23 — — US disclosed
WO-2005080988-A1 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2005-09-01 — — WO disclosed
US-20050014290-A1 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY 2005-01-20 — — US disclosed
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