Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 8/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636449 | 0.87 | CLTC (0.66) | CLTCCASP3CA12CA1CA2 | |
| SCHEMBL21404284 | 0.81 | CLTC (0.40) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL27404612 | 0.80 | CLTC (0.39) | CLTCCA12CA1CA2CA9 | |
| Ethylenediamine SCHEMBL21957845 | 0.80 | CLTC (0.39) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL1615000 | 0.75 | ALDH1A1 (0.39) | CLTCALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL21946061 | 0.75 | CLTC (0.36) | CLTCALDH1A1HSD17B10CASP6 | |
| SCHEMBL14636024 | 0.74 | CLTC (0.79) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL134056 | 0.73 | CLTC (0.34) | CLTCCA1CA2CA9MEN1 | |
| SCHEMBL16097930 | 0.73 | ALDH1A1 (0.33) | CLTCALDH1A1HSD17B10CASP6 | |
| SCHEMBL14636234 | 0.73 | CLTC (0.78) | CLTCCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |