Androstenedone

Androstenedone

SCHEMBL134061

C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 17/20 1.00
CYP3A4 P08684 1/20 1.00
LMNA P02545 2/20 0.66
MAPT P10636 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androstenedone SCHEMBL1144460 1.00 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL172864 1.00 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL12430773 1.00 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL3758714 1.00 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL14450072 1.00 CYP19A1 (1.00) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL10597170 0.99 CYP19A1 (0.97) CYP19A1CYP3A4LMNAMAPT
Androstenedone SCHEMBL4266758 0.92 CYP19A1 (0.84) CYP19A1CYP3A4LMNA
SCHEMBL6897786 0.88 CYP19A1 (0.79) CYP19A1CYP3A4LMNAMAPT
SCHEMBL8491921 0.86 CYP19A1 (0.76) CYP19A1CYP3A4LMNA
SCHEMBL6999301 0.86 CYP19A1 (0.76) CYP19A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955702-A Method for improving steroid precursor production through triacylglycerol synthesis pathway blocking, genetically engineered bacterium and application 天津科技大学 2025-05-09 CN claimed
CN-119913119-A Steroid dehydrogenase mutant and application thereof in preparation of steroid drugs 浙江工业大学 2025-05-02 CN claimed
CN-118652864-A Carbonyl reductase mutant and application and engineering bacteria thereof 武汉艾默佳华生物科技有限公司 2024-09-17 CN claimed
CN-118652860-A Alpha-ketoglutarate dependent dioxygenase mutant and application and engineering bacteria thereof 武汉艾默佳华生物科技有限公司 2024-09-17 CN claimed
CN-118530924-A Mycobacterium testosterone engineering bacteria with high yield, preparation method and application thereof 浙江工业大学 2024-08-23 CN claimed
EP-3612223-B1 TREATING MALE SENESCENCE NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) 2024-07-31 EP claimed
WO-2024131933-A1 ENGINEERED MICROBES FOR PRODUCTION OF PROGESTERONE AND URSODEOXYCHOLIC ACID BY FERMENTATION HANGZHOU ENHE BIOTECHNOLOGY CO., LTD. (CN) 2024-06-27 WO claimed
CN-118147027-A Method, strain and application for improving steroid precursor production by enhancing intracellular ATP metabolism 天津科技大学 2024-06-07 CN claimed
CN-117467629-A Method for producing baodanone by using whole cell transformation of genetically engineered bacteria and application 浙江工业大学 2024-01-30 CN claimed
CN-116574751-A Novel mycobacterium aurum recombinant expression vector and application thereof 浙江工业大学 2023-08-11 CN claimed
US-4101378-A ADDING A GLYCERIDE TO THE CULTURE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4098647-A Composition of matter and process THE UPJOHN COMPANY (US) 1978-07-04 US claimed
US-4097335-A AEROBIC CULTIVATION OF MYCOBACTERIUM FORTIUTUM THE UPJOHN COMPANY (US) 1978-06-27 US claimed
US-4062729-A Microbial transformation of steroids THE UPJOHN COMPANY (US) 1977-12-13 US claimed
US-4057469-A Process for the microbiological oxidation of steroids MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-11-08 US claimed
US-4042459-A CULTIVATING A STEROID FROM MYCOBACTERIUM THE UPJOHN COMPANY (US) 1977-08-16 US claimed
US-4039381-A STEROIDS THE UPJOHN COMPANY (US) 1977-08-02 US claimed
US-3994938-A PYROLYSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-11-30 US claimed
US-3990956-A Electrochemical reduction of α,β-unsaturated keto steroids SCHERING AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed
US-3966714-A Process for the preparation of a Δ4 -3-keto steroid 17-propiolactone SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed