Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.55 |
| ▸ | SNCA | P37840 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071461 | 1.00 | CYP19A1 (0.76) | CYP19A1CYP3A4ALDH1A1LMNASHBG | |
| Androstenedone SCHEMBL12430773 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL172864 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL3758714 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL1144460 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL14450072 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL134061 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL27795830 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNA | |
| Androstenedone SCHEMBL10597170 | 0.85 | CYP19A1 (0.97) | CYP19A1CYP3A4LMNA | |
| SCHEMBL8491921 | 0.81 | CYP19A1 (0.76) | CYP19A1CYP3A4ALDH1A1LMNASHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863906-B1 | HETEROCYCLIC DIOXETHANE SUBSTRATES, PROCESS FOR THEIR PREPARATION AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6107036-A | Heterocyclic dioxethane substrates, process for their preparation and their use | ROCHE DIAGNOSTICS GMBH (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0863906-A2 | HETEROCYCLIC DIOXETHANE SUBSTRATES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Roche Diagnostics GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997014696-A2 | HETEROCYCLIC DIOXETHANE SUBSTRATES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BOEHRINGER MANNHEIM GMBH (DE) | 1997-04-24 | — | — | WO | disclosed |