Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.64 |
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | AR | P10275 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14135303 | 0.95 | NR3C1 (0.55) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13407214 | 0.93 | NR3C1 (0.66) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL3303182 | 0.93 | NR3C1 (0.62) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL14134892 | 0.90 | HIF1A (0.57) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13407106 | 0.90 | HIF1A (0.57) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13407224 | 0.90 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13491416 | 0.86 | PGR (0.57) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13388804 | 0.85 | NR3C1 (0.64) | NR3C1PGRHIF1ALMNAAR | |
| SCHEMBL13407211 | 0.85 | NR3C1 (0.64) | NR3C1PGRHIF1ALMNAAR | |
| Hydrochloric Acid SCHEMBL3300549 | 0.85 | NR3C1 (0.64) | NR3C1PGRHIF1ALMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093685-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093685-A1 | NITRIC OXIDE RELEASING STEROIDS | NR3C1, CYP11B1, NOS1 | NR3C1 1/4885PGR 232/4885HIF1A 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.