Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407243 | 1.00 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL13407297 | 1.00 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL13266563 | 1.00 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL13266566 | 0.77 | OPRM1 (0.31) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL13266682 | 0.77 | OPRM1 (0.31) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL20073128 | 0.77 | OPRM1 (0.45) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 | |
| SCHEMBL6657904 | 0.77 | ADH1C (0.36) | — | |
| SCHEMBL18350033 | 0.77 | ADH1C (0.36) | — | |
| SCHEMBL21357944 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL13407365 | 0.76 | OPRM1 (0.33) | ALDH1A1SMN1; SMN2OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705036-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2010-04-27 | — | — | US | disclosed |