Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177514 | 0.86 | L3MBTL1 (0.54) | HDAC3HDAC1HDAC2HDAC8MAPK1 | |
| SCHEMBL19662527 | 0.85 | MAPK1 (0.46) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19662526 | 0.83 | MAPK1 (0.44) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15177515 | 0.80 | HPGD (0.51) | HDAC3NAMPTALDH1A1DRD2 | |
| SCHEMBL5492139 | 0.79 | SMN1; SMN2 (0.38) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5172973 | 0.78 | HDAC1 (0.47) | HDAC6HDAC3HDAC1MAPK1NAMPT | |
| SCHEMBL2102802 | 0.78 | HPGD (0.54) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13316693 | 0.78 | DUT (0.42) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8371252 | 0.78 | GAA (0.46) | HTTALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL3081575 | 0.77 | MAPK1 (0.81) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691787-B2 | Target molecule attachment to surfaces | SURMODICS, INC. (US) | 2010-04-06 | — | — | US | disclosed |