Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047022 | 1.00 | POLB (0.50) | POLBALDH1A1VCAM1LMNAMAPT | |
| SCHEMBL29451438 | 0.89 | POLB (0.50) | POLBALDH1A1VCAM1LMNAMAPT | |
| SCHEMBL6104167 | 0.89 | POLB (0.50) | POLBALDH1A1VCAM1LMNAMAPT | |
| SCHEMBL19071937 | 0.87 | POLB (0.51) | POLBALDH1A1VCAM1LMNAMAPT | |
| SCHEMBL12473437 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAHTTMEN1 | |
| SCHEMBL1403472 | 0.80 | ALDH1A1 (0.56) | POLBALDH1A1LMNAMAPTGAA | |
| SCHEMBL30203403 | 0.80 | ALDH1A1 (0.56) | POLBALDH1A1LMNAMAPTGAA | |
| SCHEMBL422653 | 0.79 | GAA (0.64) | POLBLMNAMAPTGAAMEN1 | |
| SCHEMBL9068677 | 0.79 | ALDH1A1 (0.54) | POLBALDH1A1LMNAMAPTGAA | |
| Methane SCHEMBL27588822 | 0.79 | ALDH1A1 (0.54) | POLBALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107406-A1 | p53 HETEROBIFUNCTIONAL CONJUGATES AND USES THEREOF | Design Therapeutics, Inc. (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-4323066-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| CN-117580835-A | MEK inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20230144211-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| WO-2022221866-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |
| CN-108395435-B | Triazolopyrimidine sulfonamide compound and preparation method and application thereof | 深圳大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-103626708-B | A kind of sulfonylurea compound | SHENZHEN UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103626708-A | Novel sulfonylurea compound | UNIV SHENZHEN | 2014-03-12 | — | — | CN | disclosed |
| CN-103073507-A | Sulfonylurea compound | UNIV SHENZHEN | 2013-05-01 | — | — | CN | disclosed |
| US-20100099662-A1 | HYDRAZONE DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144211-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | DHFR, FOLR1, MTHFD2 | POLB 2383/4885ALDH1A1 1219/4885VCAM1 787/4885 |
| US-20100099662-A1 | HYDRAZONE DERIVATIVE | GCK, GCKR, HK1 | POLB 3516/4885ALDH1A1 1260/4885VCAM1 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.