Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385827 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL31395128 | 0.86 | KDM4E (0.33) | KDM4E | |
| SCHEMBL31273758 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL15932539 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1PKMTDP1TSHR | |
| SCHEMBL31274004 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1PKMTDP1TSHR | |
| SCHEMBL14280195 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL3649763 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL3645419 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL145809 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1PKMTDP1MEN1 | |
| SCHEMBL17934494 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1PKMTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS LLC (US) | 2010-04-22 | — | — | US | disclosed |
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | PROMERUS, LLC (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | MMAB, ADH1C, OXER1 | KDM4E 3566/4885ALDH1A1 50/4885PKM 2548/4885 |
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | GNE, GALE, EXOSC5 | KDM4E 2962/4885ALDH1A1 230/4885PKM 2629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.