Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271649 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C19KDM4EKMT2A | |
| SCHEMBL13409361 | 0.81 | TRPM8 (0.41) | TRPM8ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL13409320 | 0.80 | PLAU (0.49) | TRPM8ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL3431729 | 0.80 | TRPM8 (0.40) | TRPM8ALDH1A1KMT2AMAPTATM | |
| SCHEMBL13409308 | 0.79 | ALDH1A1 (0.42) | TRPM8ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL15113591 | 0.78 | MAPT (0.42) | TRPM8ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL13409358 | 0.77 | MAPT (0.47) | TRPM8ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL13409364 | 0.74 | ALDH1A1 (0.72) | TRPM8ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL21872083 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C19KDM4EKMT2A | |
| SCHEMBL15116619 | 0.72 | PDE10A (0.47) | ALDH1A1CYP1A2CYP2C19KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |