Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409308 | 0.80 | ALDH1A1 (0.42) | MAPTATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8272616 | 0.79 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EPOLBPLAU | |
| SCHEMBL13409336 | 0.79 | ATM (0.44) | MAPTATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13409352 | 0.78 | PLAU (0.40) | MAPTATMALDH1A1KDM4EPOLB | |
| SCHEMBL13409304 | 0.77 | TRPM8 (0.51) | MAPTATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15473241 | 0.74 | ALDH1A1 (0.42) | MAPTL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL18101002 | 0.73 | ALDH1A1 (0.48) | MAPTL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL1688224 | 0.73 | ALDH1A1 (0.45) | MAPTATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12967947 | 0.72 | TP53 (0.47) | MAPTL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL12958279 | 0.70 | ALDH1A1 (0.39) | MAPTL3MBTL1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |