Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409373 | 0.81 | CYP1A2 (0.45) | ATMMAPTL3MBTL1CYP1A2CYP2A6 | |
| SCHEMBL8272295 | 0.81 | CYP1A2 (0.48) | MAPTCYP1A2CYP2A6ADRA2ANR4A2 | |
| SCHEMBL13409375 | 0.80 | ALOX5AP (0.40) | ATMMAPTL3MBTL1LRRK2SLC6A4 | |
| SCHEMBL13409358 | 0.79 | MAPT (0.47) | ATMMAPTL3MBTL1CYP1A2CYP2A6 | |
| SCHEMBL13409320 | 0.79 | PLAU (0.49) | ATMMAPTCYP1A2LRRK2ADRA2A | |
| SCHEMBL31701118 | 0.78 | LRRK2 (0.40) | ATMMAPTL3MBTL1CYP1A2LRRK2 | |
| SCHEMBL23810435 | 0.77 | TRPV4 (0.48) | ATMMAPTL3MBTL1CYP1A2LRRK2 | |
| SCHEMBL364773 | 0.77 | ATM (0.43) | ATMMAPTL3MBTL1LRRK2ADRA2A | |
| SCHEMBL13409321 | 0.76 | LRRK2 (0.36) | LRRK2ADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL13409351 | 0.76 | LRRK2 (0.36) | ATMMAPTL3MBTL1LRRK2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |