Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409398 | 0.89 | BAD (0.38) | LRRK2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8272613 | 0.84 | ADRA2A (0.37) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL13409369 | 0.82 | DRD1 (0.37) | LRRK2ATRIRAK4 | |
| SCHEMBL13409371 | 0.82 | LRRK2 (0.34) | LRRK2ATRATRIPIRAK4 | |
| SCHEMBL13409292 | 0.78 | KDM4E (0.38) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL8272975 | 0.75 | ADRA2A (0.42) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL1654872 | 0.73 | LMNA (0.43) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL13443970 | 0.72 | KDM4E (0.37) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL7820475 | 0.72 | ADRA2A (0.37) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL8372409 | 0.72 | PDE3B (0.39) | ADRA2AADRA2CADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |