Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409368 | 0.82 | LRRK2 (0.35) | LRRK2ATRIRAK4ATRIP | |
| SCHEMBL8271695 | 0.82 | SMN1; SMN2 (0.36) | LRRK2IRAK4 | |
| SCHEMBL8272974 | 0.78 | PARP1 (0.30) | — | |
| SCHEMBL13409369 | 0.78 | DRD1 (0.37) | LRRK2ATRIRAK4 | |
| SCHEMBL8276161 | 0.76 | CYP2A6 (0.34) | — | |
| SCHEMBL13409398 | 0.76 | BAD (0.38) | LRRK2 | |
| SCHEMBL15665250 | 0.73 | PARP1 (0.36) | — | |
| SCHEMBL1536439 | 0.73 | LMNA (0.41) | — | |
| SCHEMBL8277400 | 0.72 | PDE3B (0.38) | — | |
| SCHEMBL7822600 | 0.72 | ATM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |