Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 5/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409379 | 0.88 | PDGFRB (0.43) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL8300158 | 0.87 | NPC1 (0.59) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409348 | 0.86 | NPC1 (0.58) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409314 | 0.85 | ACP1 (0.54) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409339 | 0.85 | APP (0.44) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409378 | 0.84 | MAPT (0.46) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409349 | 0.83 | TRPM8 (0.49) | MAPTATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13409327 | 0.83 | BTK (0.59) | MAPTATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13409335 | 0.82 | MAPT (0.40) | MAPTATMNPC1RAB9AKDM4E | |
| SCHEMBL13409345 | 0.82 | MAPT (0.42) | MAPTATMNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |