Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335705 | 0.89 | ACP1 (0.44) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL13409339 | 0.87 | APP (0.44) | MAPTATMACP1KDM4EALDH1A1 | |
| SCHEMBL13409376 | 0.84 | MAPT (0.55) | MAPTATMACP1KDM4ESMN1; SMN2 | |
| SCHEMBL8353285 | 0.81 | ACP1 (0.43) | MAPTATMACP1MTNR1AMTNR1B | |
| SCHEMBL1536661 | 0.81 | ACP1 (0.43) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL1536561 | 0.81 | ACP1 (0.43) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL13409348 | 0.79 | NPC1 (0.58) | MAPTATMKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13409379 | 0.78 | PDGFRB (0.43) | MAPTATMACP1KDM4ESMN1; SMN2 | |
| SCHEMBL13409338 | 0.78 | MAPT (0.41) | MAPTATMACP1KDM4ESMN1; SMN2 | |
| SCHEMBL13409345 | 0.77 | MAPT (0.42) | MAPTATMACP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |