Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074157 | 0.75 | SLC22A6 (0.41) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL13409443 | 0.71 | — | — | |
| SCHEMBL10768199 | 0.71 | — | — | |
| SCHEMBL23829671 | 0.70 | — | — | |
| SCHEMBL9507774 | 0.68 | PGD (0.36) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL25407234 | 0.65 | PGD (0.42) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL25407239 | 0.65 | PGD (0.42) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL1289476 | 0.64 | — | — | |
| SCHEMBL27679696 | 0.64 | SLC22A6 (0.45) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL13409445 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691907-B2 | Methods and composition based on discovery of metabolism of nitroglycerin | DUKE UNIVERSITY (US) | 2010-04-06 | — | — | US | disclosed |