Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879242 | 0.77 | MEN1 (0.38) | SLC22A6TDP1FFAR1GPR84ALOX15 | |
| SCHEMBL10551880 | 0.77 | MEN1 (0.40) | SLC22A6TDP1FFAR1GPR84ALOX15 | |
| SCHEMBL10768199 | 0.76 | — | — | |
| SCHEMBL3168705 | 0.76 | — | — | |
| SCHEMBL3074157 | 0.75 | SLC22A6 (0.41) | PGDSLC22A6TDP1SMN1; SMN2ALOX15 | |
| SCHEMBL3880423 | 0.75 | — | — | |
| Acetaldehyde SCHEMBL11125462 | 0.74 | MMP1 (0.34) | PGDSLC22A6FFAR3TDP1FFAR1 | |
| SCHEMBL202165 | 0.73 | SLC22A6 (0.39) | PGDSLC22A6FFAR3TDP1FFAR1 | |
| SCHEMBL10742171 | 0.73 | — | — | |
| Water SCHEMBL28275948 | 0.73 | GPR84 (0.42) | TDP1GPR84ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181244-B1 | Substituted pyrido[2,3-c]pyridazin-4(1H)-ones as tumor necrosis factor alpha and phosphodiesterase 4 inhibitors | Xuanzhu Pharma Co., Ltd. (CN) | 2015-11-10 | — | — | US | disclosed |
| EP-0241423-B1 | PROCESS FOR THE PRODUCTION OF POSITIVE IMAGES | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | disclosed |
| EP-0241423-A2 | Process for the production of positive images | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |