Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409824 | 0.88 | MEN1 (0.48) | CYP3A4MEN1TSHRKMT2A | |
| SCHEMBL13409992 | 0.86 | CYP3A4 (0.47) | CYP3A4MEN1TSHRKMT2A | |
| SCHEMBL13409748 | 0.85 | CYP3A4 (0.46) | CYP3A4MEN1TSHRKMT2ACYP2D6 | |
| SCHEMBL13392336 | 0.84 | CYP3A4 (0.41) | CYP3A4MEN1TSHRKMT2ACYP2D6 | |
| SCHEMBL14078202 | 0.84 | CYP3A4 (0.41) | CYP3A4MEN1TSHRKMT2ACYP2D6 | |
| SCHEMBL14469546 | 0.83 | CYP3A4 (0.42) | CYP3A4MEN1TSHRKMT2ACYP2D6 | |
| SCHEMBL13409825 | 0.83 | MEN1 (0.44) | CYP3A4MEN1TSHRKMT2A | |
| SCHEMBL13409997 | 0.82 | MEN1 (0.46) | CYP3A4MEN1TSHRKMT2ACYP2D6 | |
| SCHEMBL13409986 | 0.82 | CYP3A4 (0.46) | CYP3A4MEN1TSHRKMT2A | |
| SCHEMBL13409133 | 0.82 | MEN1 (0.42) | CYP3A4MEN1TSHRKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093692-A1 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION SECHERING-PLOUGH CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093692-A1 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | GPR119, ATF4, GID4 | CYP3A4 2573/4885MEN1 4556/4885TSHR 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.