Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18536496 | 0.92 | — | — | |
| SCHEMBL438502 | 0.83 | SLC6A2 (0.39) | ALDH1A1MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13412949 | 0.82 | MC4R (0.38) | SLC6A3 | |
| SCHEMBL19407706 | 0.81 | SLC6A2 (0.38) | ALDH1A1MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18828088 | 0.81 | SLC6A2 (0.38) | ALDH1A1MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25725668 | 0.78 | PIK3CD (0.45) | KDM4EMAPT | |
| SCHEMBL13412945 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1MAPTCHRNA7 | |
| SCHEMBL681912 | 0.76 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMCHRNA7 | |
| SCHEMBL13290572 | 0.76 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMCHRNA7 | |
| SCHEMBL13290568 | 0.76 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100055183-A1 | TRIMEPRAZINE AND ETHOPROPAZINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOGENEX INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100055183-A1 | TRIMEPRAZINE AND ETHOPROPAZINE DERIVATIVES FOR PROMOTING BONE GROWTH | IGFBP5, BMP2, HGF | KDM4E 216/4885ALDH1A1 1534/4885MAPT 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.