Sugi Predict

Sugi Predict / Compounds / SCHEMBL134135

SCHEMBL134135

SCHEMBL134135

[c]1ccc2ccccc2c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.40
▸ HSD17B10 Q99714 4/20 0.40
▸ CYP2A6 P11509 3/20 0.40
▸ TSHR P16473 3/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ HPRT1 P00492 1/20 0.37
▸ MAPT P10636 4/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ CYP1B1 Q16678 2/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ HPGD P15428 3/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ MPI P34949 1/20 0.34
▸ CYP1A2 P05177 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537032 0.91 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL114219 0.86 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL8323603 0.84 CYP1A2 (0.38) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9957999 0.84 HPRT1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4162439 0.84 CYP1A2 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1451161 0.84 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9958010 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2254563 0.82 ESR1 (0.37) ALDH1A1HSD17B10MAPTSMN1; SMN2CYP1B1
SCHEMBL6319558 0.80 ESR1 (0.42) NPC1CYP1A2CYP3A4ESR1ESR2
SCHEMBL1274645 0.80 ALOX5 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111461-B Novel compound and application thereof in electroluminescent device 北京鼎材科技有限公司 2021-09-10 — — CN claimed
CN-109942581-B Indoline [3,2-a ] carbazole and pyridine derivative, and preparation method, application and device thereof 武汉尚赛光电科技有限公司 2020-09-04 — — CN claimed
CN-104961689-A 2,3-dihydropyrazine derivative and synthetic method thereof UNIV SHANGHAI JIAOTONG 2015-10-07 — — CN claimed
US-8900724-B2 Monobenzochrysene derivative, a material for an organic electroluminescence device containing the same, and an organic electroluminescence device using the material IDEMITSU KOSAN CO., LTD. (JP) 2014-12-02 — — US claimed
CN-102082230-B Infrared organic electroluminescent device KUNSHAN VISIONOX DISPLAY TECH 2012-09-26 — — CN claimed
CN-102082230-A Infrared organic electroluminescent device KUNSHAN VISIONOX DISPLAY TECH 2011-06-01 — — CN claimed
CN-102082231-A Green organic electroluminescent device KUNSHAN VISIONOX DISPLAY TECH 2011-06-01 — — CN claimed
CN-102082232-A Blue light organic electroluminescence device KUNSHAN VISIONOX DISPLAY TECH 2011-06-01 — — CN claimed
US-20060247439-A1 Mchir antagonists ASTRAZENECA AB (SE) 2006-11-02 — — US claimed
JP-2006501194-A — — 2006-01-12 — — JP claimed
US-5741931-A Phosphepinium salts HOECHST AG (DE) 1998-04-21 — — US claimed
US-5739372-A CYCLIZATION AT THE HYDROXY POSITION OF AN ORTHO PHENYL OR NAPHTHYL SUBSTITUTED PHENOL OR NAPHTHOL WITH A PHOSPHORUS CHLORIDE OR BROMIDE IN THE PRESENCE OF A LEWIS ACID CATALYST WITH THE ELIMINATION OF HYDROGEN CHLORIDE OR BROMIDE HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-14 — — US claimed
US-5728886-A Compounds of the phosphine group, their preparation and their use HOECHST AG (DE) 1998-03-17 — — US claimed
US-5696296-A Diphosphines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-09 — — US claimed
US-5648547-A Bis-phosphepines and processses for their preparation HOECHST AG (DE) 1997-07-15 — — US claimed
EP-0748811-A1 Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-18 — — EP claimed
EP-0748812-A1 Novel oxaphosphorines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-18 — — EP claimed
EP-0703240-A1 Bis-phosphepines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-27 — — EP claimed
US-5498797-A Bis(phosphinozlkoxy)biaryl compounds and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-12 — — US claimed
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247439-A1 Mchir antagonists MCHR1, HCRTR1, MC3R ALDH1A1 2548/4885HSD17B10 544/4885CYP2A6 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.