Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781961 | 0.97 | ALDH1A1 (0.48) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL16922981 | 0.93 | MAPK1 (0.45) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL16922978 | 0.93 | MAPK1 (0.45) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL12781938 | 0.93 | MAPK1 (0.45) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL13312965 | 0.92 | PDK2 (0.45) | ALDH1A1MAPK1PDK2SMN1; SMN2AGTR1 | |
| SCHEMBL15715825 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL12781965 | 0.91 | PDK2 (0.46) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL15678833 | 0.90 | MAPK1 (0.42) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL12635475 | 0.90 | MAPK1 (0.48) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 | |
| SCHEMBL15553456 | 0.88 | PDK2 (0.44) | ALDH1A1MAPK1PDK2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318948-B2 | Fluorene derivatives and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8318948-B2 | Fluorene derivatives and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-11-27 | — | — | US | disclosed |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| WO-2008069586-A1 | NEW FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, FTO | ALDH1A1 779/4885MAPK1 2921/4885PDK2 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.