Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | YARS1 | P54577 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407296 | 0.85 | SLC7A5 (0.50) | SLC7A5ESR1ESR2HDAC8LNPEP | |
| SCHEMBL12562991 | 0.85 | SLC7A5 (0.50) | SLC7A5ESR1ESR2HDAC8LNPEP | |
| SCHEMBL13416627 | 0.85 | SLC7A5 (0.50) | SLC7A5ESR1ESR2HDAC8TAAR1 | |
| SCHEMBL13416262 | 0.84 | SLC7A5 (0.49) | SLC7A5ESR1ESR2HDAC8LNPEP | |
| SCHEMBL13416629 | 0.84 | SLC7A5 (0.49) | SLC7A5ESR1ESR2HDAC8LNPEP | |
| SCHEMBL17738628 | 0.80 | SLC7A5 (0.65) | SLC7A5ESR1ESR2HDAC8TAAR1 | |
| SCHEMBL13396367 | 0.80 | SLC7A5 (0.44) | SLC7A5ESR1ESR2HDAC8LNPEP | |
| SCHEMBL13416628 | 0.80 | SLC7A5 (0.53) | SLC7A5ESR1ESR2HDAC8TAAR1 | |
| SCHEMBL16607621 | 0.76 | SLC7A5 (0.59) | SLC7A5ESR1ESR2HDAC8TAAR1 | |
| SCHEMBL9513958 | 0.76 | SLC7A5 (0.59) | SLC7A5ESR1ESR2HDAC8TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | SLC7A5 4181/4885ESR1 1712/4885ESR2 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.