Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13811457 | 0.87 | LTA4H (0.39) | CYP2C9CYP2C19CA1CA2ALDH1A1 | |
| SCHEMBL17655054 | 0.87 | LTA4H (0.39) | CYP2C9CYP2C19CA1CA2ALDH1A1 | |
| SCHEMBL31265343 | 0.82 | MMP3 (0.46) | MMP3BCL2L1CYP1A2GAACYP2C9 | |
| SCHEMBL9972334 | 0.77 | LTA4H (0.43) | CA1CA2ALDH1A1TAAR1LMNA | |
| SCHEMBL20873711 | 0.77 | ALDH1A1 (0.56) | MMP3BCL2L1CYP1A2GAACYP2C9 | |
| Biphenyl SCHEMBL7925417 | 0.74 | ALDH1A1 (0.53) | MMP3BCL2L1CYP1A2CA1CA2 | |
| SCHEMBL9942628 | 0.74 | MAOB (0.37) | CYP1A2CYP2C19CA1CA2CA9 | |
| Biphenyl SCHEMBL9189599 | 0.74 | MMP3 (0.61) | MMP3BCL2L1CYP1A2CYP2C19CA1 | |
| SCHEMBL27432466 | 0.72 | ALDH1A1 (0.50) | MMP3BCL2L1CYP1A2GAACYP2C9 | |
| SCHEMBL17049457 | 0.71 | LTA4H (0.47) | MMP3BCL2L1CYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039789-A1 | SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |