SCHEMBL134199

SCHEMBL134199

[c]1ccccc1OCC1CO1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 4/20 0.54
GLA P06280 1/20 0.54
TP53 P04637 3/20 0.49
TSHR P16473 3/20 0.49
HIF1A Q16665 2/20 0.49
CYP3A4 P08684 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
PKM P14618 2/20 0.40
CYP1A2 P05177 1/20 0.40
PPARG P37231 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
FGFR1 P11362 1/20 0.36
SRC P12931 1/20 0.36
MGLL Q99685 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20138462 0.83 MEN1 (0.43) TDP1ALDH1A1GLATP53TSHR
SCHEMBL3013228 0.82 POLB (0.43) ALDH1A1TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL5658824 0.81 NPC1 (0.41) SMN1; SMN2HPGDMGLL
SCHEMBL12097795 0.81 NTRK1 (0.34) TDP1ALDH1A1GLA
SCHEMBL28000445 0.79 HTR2A (0.61) CYP3A4CYP1A2ADRB2HTR1ASLC6A2
SCHEMBL1221903 0.78 RIPK1 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL14864125 0.77 ALDH1A1 (0.49) TDP1ALDH1A1GLATP53TSHR
SCHEMBL679937 0.77 ALDH1A1 (0.78) TDP1ALDH1A1GLATP53TSHR
SCHEMBL22357196 0.77 ALDH1A1 (0.78) TDP1ALDH1A1GLATP53TSHR
SCHEMBL12482533 0.76 MCHR1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120013834-A1 LIQUID CRYSTAL FILM LG CHEM, LTD. (KR) 2012-01-19 US claimed
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-11-25 US claimed
EP-2214621-A2 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M Innovative Properties Company (US) 2010-08-11 EP claimed
US-7695895-B2 photopolymerizable unsaturated binder obtained by adding unsaturated monobasic acid polyfunctional epoxy resin to form epoxy adduct and allowing epoxy adduct and polybasic acid anhydride to react; color filters, liquid crystal displays, image sensors TOPPAN PRINTING CO., LTD. (JP) 2010-04-13 US claimed
WO-2009058854-A2 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-05-07 WO claimed
EP-1906243-A1 ALKALINE-DEVELOPABLE PHOTOSENSITIVE COLORED COMPOSITION Toppan Printing Co., Ltd. (JP) 2008-04-02 EP claimed
US-20070292805-A1 photopolymerizable unsaturated binder obtained by adding unsaturated monobasic acid polyfunctional epoxy resin to form epoxy adduct and allowing epoxy adduct and polybasic acid anhydride to react; color filters, liquid crystal displays, image sensors ADEKA CORPORATION (JP) 2007-12-20 US claimed
US-20070023288-A1 Method of forming multi-layered coating film KANSAI PAINT CO., LTD. (JP) 2007-02-01 US claimed
US-6713589-B2 GLASS TRANSITION TEMPERATURE, LOW MOISTURE ABSORPTION, ADHESION HITACHI CHEMICAL COMPANY, LTD. (JP) 2004-03-30 US claimed
US-6660811-B2 Curing agent and oligomers or polymers derived from the reaction product of an aromatic aldehyde and a phenolic compound, with the phenolic hydroxyl groups converted to glycidyloxy groups; semiconductor, electronic sealants DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-12-09 US claimed
US-20020065386-A1 Glass transition temperature, low moisture absorption, adhesion HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-05-30 US claimed
US-6329492-B1 USEFUL AS MATERIAL FOR ENCAPSULATING ELECTRONIC DEVICES, FOR LAMINATION OR FOR ADHESION; CURING AGENT FOR EPOXY RESINS HITACHI CHEMICAL COMPANY, LTD. (JP) 2001-12-11 US claimed
US-6156865-A Flame retardant thermosetting resin composition NEC CORPORATION (JP) 2000-12-05 US claimed
EP-0567066-B1 Resin composition for aqueous paints KANSAI PAINT CO LTD (JP) 2000-07-12 EP claimed
US-5369150-A Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1994-11-29 US claimed
US-5369151-A Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1994-11-29 US claimed
EP-0567066-A2 Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1993-10-27 EP claimed
EP-0336475-B1 1,6-DIAZASPIRO (4,4)NONANE-2,7-DIONE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-12-23 EP claimed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US claimed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS PITHD1, DDX24, DACH1 TDP1 1898/4885ALDH1A1 3070/4885GLA 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.