SCHEMBL134200

SCHEMBL134200

[c]1ccc(OCC2CO2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 4/20 0.58
TSHR P16473 4/20 0.58
TP53 P04637 3/20 0.58
HIF1A Q16665 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CYP3A4 P08684 1/20 0.58
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
PKM P14618 2/20 0.56
CYP1A2 P05177 1/20 0.56
PPARG P37231 1/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 1/20 0.56
GLA P06280 1/20 0.50
FGFR1 P11362 1/20 0.38
SRC P12931 1/20 0.38
HRH3 Q9Y5N1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27904123 1.00 TDP1 (0.66) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL3958467 1.00 TDP1 (0.66) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL50264 0.85 TDP1 (0.79) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL20677146 0.85 TDP1 (0.79) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL21094081 0.85 TDP1 (0.79) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL20590552 0.84 TDP1 (0.47) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL5707438 0.82 ALDH1A1 (0.51) TDP1ALDH1A1TSHRTP53HIF1A
SCHEMBL9055789 0.82 TDP1 (0.46) TDP1ALDH1A1TSHRTP53HIF1A
Water SCHEMBL11032953 0.82 TDP1 (0.68) TDP1ALDH1A1TSHRTP53HIF1A
Water SCHEMBL6248999 0.82 TDP1 (0.96) TDP1ALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209483-A Benzofuran derivative and preparation method and application thereof 扬州中宝药业股份有限公司 2023-12-12 CN claimed
CN-114479353-A Topological interlocking liquid crystal epoxy heat-conducting resin and preparation method and application thereof 中山大学 2022-05-13 CN claimed
CN-107974080-B Polyamide moulding compositions and multilayer structures made therefrom EMS专利股份公司 2021-07-20 CN claimed
EP-3604320-A1 FLAME RETARDANT PHOSPHOROUS FUNCTIONAL POLYETHER CARBONATE POLYOLS AND METHOD FOR THEIR PREPARATION Covestro Deutschland AG (DE) 2020-02-05 EP claimed
EP-3312224-B1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM EMS PATENT AG (CH) 2018-12-26 EP claimed
EP-3312224-A1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM EMS-PATENT AG (CH) 2018-04-25 EP claimed
CN-106279577-A A kind of composite for ultrasonic washing machine 无锡市永亿精密铸造有限公司 2017-01-04 CN claimed
US-20120013834-A1 LIQUID CRYSTAL FILM LG CHEM, LTD. (KR) 2012-01-19 US claimed
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-11-25 US claimed
EP-2214621-A2 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M Innovative Properties Company (US) 2010-08-11 EP claimed
US-6156865-A Flame retardant thermosetting resin composition NEC CORPORATION (JP) 2000-12-05 US claimed
EP-0567066-B1 Resin composition for aqueous paints KANSAI PAINT CO LTD (JP) 2000-07-12 EP claimed
US-5982056-A STATOR OF ROTATING MACHINE HITACHI, LTD. (JP) 1999-11-09 US claimed
EP-0810249-A2 Thermosetting resin composition, electrically insulated coil, electric rotating machine and method for producing same HITACHI, LTD. (JP) 1997-12-03 EP claimed
US-5369150-A Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1994-11-29 US claimed
US-5369151-A Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1994-11-29 US claimed
EP-0567066-A2 Resin composition for aqueous paints KANSAI PAINT CO., LTD. (JP) 1993-10-27 EP claimed
EP-0336475-B1 1,6-DIAZASPIRO (4,4)NONANE-2,7-DIONE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-12-23 EP claimed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US claimed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS PITHD1, DDX24, DACH1 TDP1 1898/4885ALDH1A1 3070/4885TSHR 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.