Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357215 | 0.90 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1HRH1LMNA | |
| SCHEMBL2357242 | 0.78 | SMN1; SMN2 (0.33) | MEN1KMT2AALDH1A1HRH1LMNA | |
| SCHEMBL13421525 | 0.73 | EGFR (0.38) | MEN1KMT2ACYP1A2CYP3A4TSHR | |
| SCHEMBL12013167 | 0.69 | LMNA (0.44) | MEN1KMT2AALDH1A1HRH1LMNA | |
| SCHEMBL13422031 | 0.68 | SMN1; SMN2 (0.36) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12012897 | 0.68 | HRH1 (0.41) | MEN1KMT2AALDH1A1HRH1LMNA | |
| SCHEMBL3318342 | 0.68 | HRH1 (0.41) | MEN1KMT2AALDH1A1HRH1LMNA | |
| SCHEMBL3726443 | 0.68 | CCNE1 (0.36) | ALDH1A1HRH1TRPM8HRH4 | |
| SCHEMBL3726442 | 0.68 | CCNE1 (0.36) | ALDH1A1HRH1TRPM8HRH4 | |
| SCHEMBL13422048 | 0.68 | CNR2 (0.37) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042699-A1 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-15 | — | — | WO | disclosed |