Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482006 | 0.91 | CYP2A6 (0.58) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4071129 | 0.88 | RAB9A (0.51) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL30253453 | 0.86 | CYP2A6 (0.56) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10456611 | 0.86 | CYP2A6 (0.56) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL12532349 | 0.85 | NPC1 (0.68) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9699266 | 0.85 | CYP2A6 (0.66) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2758626 | 0.85 | CYP2A6 (0.55) | CYP2A6RAB9ANPC1CYP1A2KDM4E | |
| SCHEMBL12520194 | 0.85 | CYP2A6 (0.59) | CYP2A6RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2758624 | 0.85 | PTPN1 (0.68) | CYP2A6RAB9ANPC1CYP1A2KDM4E | |
| SCHEMBL9244584 | 0.83 | CYP2A6 (0.53) | CYP2A6RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7670505-B2 | Compounds comprising 2,6-naphthyl groups | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | SCO2, MT-CO1, CBR1 | CYP2A6 500/4885RAB9A 3714/4885NPC1 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.