SCHEMBL28482006

SCHEMBL28482006

CC(=O)CC(=O)c1ccc2cc(C)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CYP1A2 P05177 4/20 0.46
RAB9A P51151 7/20 0.46
NPC1 O15118 6/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PTPN1 P18031 1/20 0.43
MAPT P10636 1/20 0.42
CTNNB1 P35222 2/20 0.42
WNT3A P56704 2/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9699266 0.95 CYP2A6 (0.66) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL13422352 0.91 CYP2A6 (0.58) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL2758626 0.84 CYP2A6 (0.55) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL2774094 0.84 SMN1; SMN2 (0.72) SMN1; SMN2HPGDKDM4ECYP1A2RAB9A
SCHEMBL10456611 0.81 CYP2A6 (0.56) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL30253453 0.81 CYP2A6 (0.56) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL3035986 0.81 NPC1 (0.67) SMN1; SMN2HPGDKDM4ERAB9ANPC1
SCHEMBL4071129 0.80 RAB9A (0.51) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL2758624 0.80 PTPN1 (0.68) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2
SCHEMBL12520194 0.80 CYP2A6 (0.59) CYP2A6SMN1; SMN2HPGDKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909023-A High pressure condensate formation in the manufacture of purified aromatic carboxylic acids BP北美公司 2020-11-10 CN disclosed