Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL8008161 | 0.96 | — | — | |
| Glycolic Acid SCHEMBL10727608 | 0.92 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL4522823 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL991430 | 0.91 | — | — | |
| Glycolic Acid SCHEMBL2488158 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL15441504 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL26512 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL1002389 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL21297631 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL4555780 | 0.91 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245031-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE-INHIBITING BIOCHEMICAL SOLUTIONS, METHODS, AND APPARATUS FOR APPLYING TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2025-11-27 | — | — | WO | claimed |
| CN-119350289-A | Method for preparing high-purity 1, 4-dioxane-2-ketone at low cost | 青岛科技大学 | 2025-01-24 | — | — | CN | claimed |
| CN-114350736-B | Method for increasing astaxanthin diester content in haematococcus pluvialis culture | 万华化学(四川)有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-117334811-A | Negative electrode material, preparation method thereof and sodium ion battery | 深圳市贝特瑞新能源技术研究院有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-107250318-B | Super concentrate additive solution compositions | 布拉斯通产品公司 | 2023-10-27 | — | — | CN | claimed |
| EP-3739017-B1 | METHOD OF PREVENTING CORROSION OF HEAT TRANSFER SYSTEM | PRESTONE PRODUCTS CORP (US) | 2023-06-07 | — | — | EP | claimed |
| WO-2023091370-A1 | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS | COMERA LIFE SCIENCES, INC. (US) | 2023-05-25 | — | — | WO | claimed |
| US-20230078678-A1 | FORMULATIONS OF HUMAN ANTI-TSLP ANTIBODIES AND METHODS OF TREATING ATOPIC DERMATITIS | AMGEN INC. | 2023-03-16 | — | — | US | claimed |
| US-11560794-B2 | Solvent-stabilized colorimetric detection of amine-based additives | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-01-24 | — | — | US | claimed |
| US-11555787-B2 | Polymer-enhanced colorimetric detection of amine-based additives | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-01-17 | — | — | US | claimed |
| US-5776473-A | Razor comfort strip with alpha-hydroxy acid additive | WARNER-LAMBERT COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| EP-0577059-B1 | Oxychlorination catalyst, process for preparing the catalyst and method of oxychlorination with use of the catalyst | SUMITOMO CHEMICAL CO (JP) | 1997-09-24 | — | — | EP | claimed |
| EP-0573610-B1 | SYNTHETIC SPINELS AND PROCESSES FOR MAKING THEM | INTERCAT INC (US) | 1997-06-04 | — | — | EP | claimed |
| US-5545604-A | CALCINING SOLID SOLUTION COMPRISING SPRAY DRIED MIXTURE OF ALUMINA SOL, MAGNESIUM COMPOUND AND BASTNAESITE | INTERCAT, INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5334789-A | Oxychlorination of olefin or aromatic hydrocarbon with oxygen and hydrogen chloride in presence of catalyst containing compounds of palladium, copper, vanadium on carrier | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-02 | — | — | US | claimed |
| EP-0573610-A4 | — | — | 1994-03-23 | — | — | EP | claimed |
| EP-0577059-A1 | Oxychlorination catalyst, process for preparing the catalyst and method of oxychlorination with use of the catalyst | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-01-05 | — | — | EP | claimed |
| EP-0573610-A1 | SYNTHETIC SPINELS AND PROCESSES FOR MAKING THEM. | INTERCAT INC (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992014546-A1 | SYNTHETIC SPINELS AND PROCESSES FOR MAKING THEM | INTERCAT, INC. (US) | 1992-09-03 | — | — | WO | claimed |
| US-5108979-A | Calcination to from solid solution of oxides | INTERCAT, INC. (US) | 1992-04-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230078678-A1 | FORMULATIONS OF HUMAN ANTI-TSLP ANTIBODIES AND METHODS OF TREATING ATOPIC DERMATITIS | TSLP, IL5, ORAI1 | CA4 2428/4885OR51E2 4287/4885CASP1 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.