Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423252 | 0.97 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL13423257 | 0.97 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL13423232 | 0.97 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL13423246 | 0.96 | PDK2 (0.57) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL13423239 | 0.94 | PDK2 (0.48) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL13423240 | 0.91 | PDK2 (0.50) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL1552743 | 0.87 | PDK2 (0.66) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL133477 | 0.87 | PDK2 (0.66) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL14096679 | 0.86 | PDK2 (0.50) | PDK2ATMTDP1L3MBTL1CNR2 | |
| SCHEMBL13423313 | 0.84 | PDK2 (0.48) | PDK2L3MBTL1CNR2ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683229-B2 | truxene and isotruxene derivatives, in particular spirotruxene and spiroisotruxene derivatives; use thereof in organic electronic devices, in particular organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-20080093980-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080093980-A1 | Organic Electroluminescent Device | OXER1, NR3C2, OXTR | PDK2 921/4885ATM 2905/4885TDP1 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.