Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 16/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423240 | 0.97 | PDK2 (0.50) | PDK2ATMTDP1L3MBTL1HTR7 | |
| SCHEMBL13423231 | 0.94 | PDK2 (0.56) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL13423257 | 0.91 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL13423232 | 0.91 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL13423252 | 0.91 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL13423246 | 0.90 | PDK2 (0.57) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL22175362 | 0.88 | PDK2 (0.50) | PDK2ATMTDP1L3MBTL1HTR7 | |
| SCHEMBL134285 | 0.87 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL29114 | 0.87 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 | |
| SCHEMBL134286 | 0.87 | PDK2 (0.58) | PDK2ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683229-B2 | truxene and isotruxene derivatives, in particular spirotruxene and spiroisotruxene derivatives; use thereof in organic electronic devices, in particular organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-20080093980-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080093980-A1 | Organic Electroluminescent Device | OXER1, NR3C2, OXTR | PDK2 921/4885ATM 2905/4885TDP1 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.