Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423344 | 0.93 | THRB (0.49) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL11650141 | 0.93 | THRB (0.49) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL13423349 | 0.90 | MAPK1 (0.46) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL13779725 | 0.87 | MAPK1 (0.44) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL18492271 | 0.87 | ADRB2 (0.53) | ADRB2ADRB1ADRB3THRBSMN1; SMN2 | |
| SCHEMBL19456757 | 0.87 | THRB (0.43) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL18392498 | 0.86 | TSHR (0.43) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL18492364 | 0.85 | MAPK1 (0.49) | TSHRMAPK1HIF1AADRB2ADRB1 | |
| SCHEMBL19129048 | 0.84 | SOD1 (0.43) | LMNATSHRMAPK1HIF1AADRB2 | |
| SCHEMBL16647277 | 0.84 | THRB (0.41) | LMNATSHRMAPK1HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678433-B2 | Sealant for liquid crystal and liquid-crystal display cell made with the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-03-16 | — | — | US | disclosed |