Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.50 |
| ▸ | BCL9 | O00512 | 3/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525549 | 0.91 | FDPS (0.50) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Royleanone SCHEMBL21291506 | 0.83 | CYP3A4 (0.44) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Royleanone SCHEMBL16006778 | 0.83 | CYP3A4 (0.44) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL13201767 | 0.74 | FDPS (0.53) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL13197140 | 0.74 | FDPS (0.53) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL21291505 | 0.68 | EP300 (0.40) | FDPSALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL22861898 | 0.67 | EP300 (0.42) | FDPSGGPS1CYP19A1 | |
| SCHEMBL22861899 | 0.67 | EP300 (0.42) | FDPSGGPS1CYP19A1 | |
| SCHEMBL12301455 | 0.67 | FDPS (0.68) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL9923661 | 0.67 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056615-A1 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | DSM IP ASSETS B.V. (NL) | 2010-03-04 | — | — | US | disclosed |
| US-20100056615-A1 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | DSM IP ASSETS B.V. (NL) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056615-A1 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | TNF, VDR, CYP24A1 | FDPS 56/4885BCL9 2980/4885CTNNB1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.