SCHEMBL13201767

SCHEMBL13201767

CC(C)C1=CC2=C(C(=O)C1=O)C1(C(=O)O)CCCC(C)(C)[C@@H]1CC2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 16/20 0.53
▸ BCL9 O00512 3/20 0.51
▸ CTNNB1 P35222 3/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ CYP3A4 P08684 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ HPGD P15428 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ PTGES O14684 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ PNLIP P16233 1/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ GSTO1 P78417 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ USP2 O75604 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13197140 1.00 FDPS (0.53) FDPSBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL29574656 0.82 FDPS (0.50) FDPSCYP3A4MAPTMEN1KMT2A
SCHEMBL12557643 0.76 FDPS (0.45) FDPSCYP3A4MAPTMEN1KMT2A
SCHEMBL30525549 0.76 FDPS (0.50) FDPSBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL13423517 0.74 FDPS (0.50) FDPSBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL29525911 0.69 FDPS (0.71) FDPSBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL1439596 0.69 FDPS (0.71) FDPSBCL9CTNNB1ALDH1A1CYP3A4
SCHEMBL15732245 0.68 EP300 (0.46) FDPSCYP3A4MAPTMEN1ALOX12
Carnosic Acid SCHEMBL9923661 0.67 FDPS (1.00) FDPSBCL9CTNNB1ALDH1A1CYP3A4
Carnosic Acid SCHEMBL12590737 0.67 FDPS (1.00) FDPSBCL9CTNNB1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299274-B2 Process for producing carnosol from carnosic acid using hydrogen peroxide or peracids DSM IP ASSETS B.V. (NL) 2012-10-30 — — US disclosed
US-20100217036-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID DSM IP ASSETS B.V. (NL) 2010-08-26 — — US disclosed
US-20100210859-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID USING HYDROGEN PEROXIDE OR PERACIDS DSM IP ASSETS B.V. (NL) 2010-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217036-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID CROCC, ACLY, COASY FDPS 4/4885BCL9 4423/4885CTNNB1 4830/4885
US-20100210859-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID USING HYDROGEN PEROXIDE OR PERACIDS FECH, CAT, CROCC FDPS 73/4885BCL9 4356/4885CTNNB1 4800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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