Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | BCL2 | P10415 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 9/20 | 0.33 |
| ▸ | ABL1 | P00519 | 8/20 | 0.33 |
| ▸ | HCK | P08631 | 8/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.33 |
| ▸ | EGFR | P00533 | 7/20 | 0.33 |
| ▸ | KDR | P35968 | 7/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.33 |
| ▸ | MTOR | P42345 | 7/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 7/20 | 0.33 |
| ▸ | PRKDC | P78527 | 7/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424098 | 0.92 | SRC (0.36) | SRCABL1HCKPIK3CDEGFR | |
| SCHEMBL13423953 | 0.89 | POLB (0.34) | MDM2MCL1BCL2SRCABL1 | |
| SCHEMBL15477984 | 0.84 | HCAR3 (0.37) | MDM2MCL1BCL2PIK3CAMTOR | |
| SCHEMBL13423950 | 0.81 | ALDH1A1 (0.46) | MDM2MCL1BCL2KDM4EALDH1A1 | |
| SCHEMBL13423925 | 0.79 | SRC (0.34) | SRCABL1HCKPIK3CDEGFR | |
| SCHEMBL13423875 | 0.79 | MALT1 (0.38) | KDRPIK3CABRD4CREBBP | |
| SCHEMBL13423955 | 0.74 | RORC (0.36) | PIK3CGBRD4CREBBP | |
| SCHEMBL13424097 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1PIK3CAMTORPI4KB | |
| SCHEMBL13423945 | 0.73 | RORC (0.38) | BRD4CREBBP | |
| SCHEMBL13423956 | 0.70 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043676-A1 | TETRA-AZA-HETEROCYCLES AS PHOSPHATIDYLINOSITOL-3-KINASES (PI3-KINASES) INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-22 | — | — | WO | disclosed |