Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (S)-Enastron SCHEMBL5177968 | 0.87 | ALDH1A1 (0.72) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL15976552 | 0.83 | ALDH1A1 (0.74) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL7820460 | 0.82 | GPR174 (0.74) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL5177780 | 0.81 | KIF11 (0.48) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL13425486 | 0.81 | KMT2A (0.59) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL13426046 | 0.81 | KIF11 (0.46) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL13425478 | 0.77 | MEN1 (0.55) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL8076297 | 0.75 | KIF11 (0.56) | GAAMAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL22388510 | 0.72 | GPR174 (1.00) | GAAKMT2AMEN1MAPTGPR174 | |
| SCHEMBL18724770 | 0.72 | KMT2A (0.60) | GAAKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |