Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 11/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426713 | 0.90 | BRAF (0.49) | FYNBRAFKDRPOLBRAB9A | |
| SCHEMBL3433187 | 0.82 | RAB9A (0.37) | BRAFPOLBRAB9ATNIK | |
| SCHEMBL13426106 | 0.81 | FYN (0.46) | FYNBRAFKDRPOLBRAB9A | |
| SCHEMBL3433175 | 0.81 | KCNH2 (0.47) | FYNBRAFPIM2PIM1PIM3 | |
| SCHEMBL3399291 | 0.81 | CYP1A2 (0.47) | FYNBRAF | |
| SCHEMBL13426028 | 0.80 | AKT1 (0.39) | FYNBRAFKDRPOLBRAB9A | |
| SCHEMBL3392166 | 0.80 | CYP1A2 (0.44) | BRAFPOLBRAB9ATNIK | |
| SCHEMBL3397300 | 0.79 | EIF2AK2 (0.41) | POLBRAB9ACLK2CLK3DYRK1A | |
| SCHEMBL13426793 | 0.78 | CYP1A2 (0.47) | FYNBRAFKDR | |
| SCHEMBL13426360 | 0.77 | NOS2 (0.44) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |