Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426803 | 0.89 | CLK4 (0.41) | EIF2AK2DYRK1ACLK4DYRK1BMAPK14 | |
| SCHEMBL3433187 | 0.83 | RAB9A (0.37) | POLBRAB9A | |
| SCHEMBL13426360 | 0.81 | NOS2 (0.44) | CLK4MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL13425542 | 0.80 | CLK4 (0.41) | DYRK1ACLK4DYRK1BMAPK14MAPK13 | |
| SCHEMBL13425809 | 0.79 | KCNH2 (0.49) | DYRK1ACLK4MAPK14MAPK13RAF1 | |
| SCHEMBL13425732 | 0.79 | CLK4 (0.45) | DYRK1ACLK4DYRK1BMAPK14MAPK13 | |
| SCHEMBL13425541 | 0.79 | FYN (0.51) | DYRK1APOLBRAB9ACLK2CLK3 | |
| SCHEMBL13425806 | 0.77 | CDC7 (0.47) | CLK4CDC7CDK2 | |
| SCHEMBL13425775 | 0.76 | GPR84 (0.38) | IGF1RPOLBRAB9A | |
| SCHEMBL13425543 | 0.75 | NR1H4 (0.37) | CLK4IGF1RPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |