SCHEMBL13425670

SCHEMBL13425670

Cc1ccccc1-c1cnnc(NCc2cc(-c3ccccc3)[nH]n2)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
CLK4 Q9HAZ1 3/20 0.38
TSHR P16473 2/20 0.38
CYP2C19 P33261 2/20 0.38
TP53 P04637 2/20 0.38
CYP2D6 P10635 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
VCP P55072 1/20 0.37
CYP3A4 P08684 2/20 0.37
RAB9A P51151 5/20 0.37
POLB P06746 1/20 0.37
CYP11B2 P19099 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 2/20 0.36
MAPT P10636 2/20 0.36
USP2 O75604 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13426075 0.94 HPGD (0.37) CYP1A2CLK4TSHRCYP2C19TP53
SCHEMBL13425769 0.93 RAB9A (0.35) CYP1A2CYP2C19CYP2D6VCPCYP3A4
SCHEMBL13425701 0.90 ALDH1A1 (0.38) CYP1A2CYP2C19TP53CYP2D6CYP3A4
SCHEMBL13425718 0.90 HPGD (0.36) TP53RAB9APOLBCYP11B2SMN1; SMN2
SCHEMBL13425768 0.90 RAB9A (0.39) RAB9APOLBCYP11B2SMN1; SMN2ALOX15
SCHEMBL3433187 0.89 RAB9A (0.37) CYP1A2CYP2C19CYP2D6VCPCYP3A4
SCHEMBL13425663 0.87 RAB9A (0.46) RAB9APOLBCYP11B2SMN1; SMN2MAPT
SCHEMBL13425672 0.87 ATR (0.39) VCPRAB9APOLBCYP11B2MAPT
SCHEMBL13426077 0.87 NR1H2 (0.37) TP53RAB9APOLBALOX15MAPT
SCHEMBL3394036 0.87 ALOX15 (0.45) CYP1A2TSHRCYP2C19TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed