Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425783 | 0.88 | KCNH2 (0.40) | KCNH2FASNTNIKALDH1A1 | |
| SCHEMBL13425820 | 0.87 | KCNH2 (0.40) | DYRK1AMAPTNPC1PKMMEN1 | |
| SCHEMBL13425758 | 0.87 | TNIK (0.43) | KCNH2FASNTNIK | |
| SCHEMBL13426242 | 0.87 | KCNH2 (0.39) | NPC1MEN1RAB9AKMT2APOLB | |
| SCHEMBL13426043 | 0.87 | KCNH2 (0.43) | KCNH2TNIKALDH1A1 | |
| SCHEMBL3393484 | 0.85 | ACP1 (0.39) | DYRK1AMAPTNPC1MEN1RAB9A | |
| SCHEMBL13425814 | 0.81 | GABRG2 (0.40) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL3393631 | 0.80 | KCNH2 (0.54) | DYRK1AMAPTNPC1PKMMEN1 | |
| SCHEMBL13425781 | 0.79 | GABRG2 (0.38) | MAPTMEN1KMT2APOLBKCNH2 | |
| SCHEMBL13426190 | 0.79 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |