Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425783 | 0.90 | KCNH2 (0.40) | KCNH2CLK4TNIKCYP11B1CYP11B2 | |
| SCHEMBL13426242 | 0.89 | KCNH2 (0.39) | NPC1RAB9AMAPK14MEN1KMT2A | |
| SCHEMBL13425758 | 0.89 | TNIK (0.43) | KCNH2TNIKCYP11B1CYP11B2 | |
| SCHEMBL13426043 | 0.89 | KCNH2 (0.43) | MAPK1KCNH2CLK4TNIK | |
| SCHEMBL13425754 | 0.85 | DYRK1A (0.37) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13425761 | 0.84 | CHEK1 (0.40) | KCNH2 | |
| SCHEMBL13425759 | 0.84 | CAMKK2 (0.51) | — | |
| SCHEMBL13425814 | 0.83 | GABRG2 (0.40) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL13425781 | 0.81 | GABRG2 (0.38) | MAPTMEN1KMT2AKCNH2CLK4 | |
| SCHEMBL13426190 | 0.81 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |