Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425878 | 0.85 | SMN1; SMN2 (0.38) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13425444 | 0.85 | MAPT (0.39) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13425908 | 0.84 | L3MBTL1 (0.39) | MAPTALDH1A1LMNABCL2MAPK1 | |
| SCHEMBL13426424 | 0.84 | F2RL1 (0.41) | RAB9ANPC1 | |
| SCHEMBL13426524 | 0.84 | MAPT (0.47) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13426422 | 0.84 | TSHR (0.40) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3396698 | 0.83 | GABRA1 (0.44) | ALDH1A1RAB9ASMN1; SMN2RAD51SCN4A | |
| SCHEMBL13426455 | 0.83 | HTT (0.45) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13425786 | 0.81 | F2RL3 (0.39) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13425963 | 0.81 | RARG (0.42) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |