Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425902 | 0.83 | MAPT (0.44) | GABRA1GABRB2RAD51SMN1; SMN2RAB9A | |
| SCHEMBL3395630 | 0.82 | HDAC6 (0.44) | RAD51SCN4AALDH1A1MEN1KMT2A | |
| SCHEMBL3393979 | 0.81 | PDE4B (0.50) | GABRA1GABRB2RAD51SMN1; SMN2RAB9A | |
| SCHEMBL3395758 | 0.71 | GRK6 (0.41) | SMN1; SMN2RAB9ACASP1PHGDHALDH1A1 | |
| SCHEMBL21198256 | 0.70 | MAPT (0.44) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL18127956 | 0.70 | SCN4A (0.65) | GABRA1GABRB2SMN1; SMN2RAB9ASCN4A | |
| SCHEMBL17673651 | 0.69 | RAB9A (0.53) | GABRA1GABRB2SMN1; SMN2RAB9ASCN4A | |
| SCHEMBL15713898 | 0.69 | SCN4A (0.44) | RAD51SMN1; SMN2RAB9ASCN4ACASP1 | |
| SCHEMBL15713895 | 0.69 | SCN4A (0.44) | GABRA1GABRB2RAD51SMN1; SMN2RAB9A | |
| SCHEMBL2864311 | 0.68 | ELANE (0.54) | SMN1; SMN2GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |