Sugi Predict

Sugi Predict / Compounds / SCHEMBL1342671

SCHEMBL1342671

SCHEMBL1342671

C/C=C(/C#N)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 11/20 0.53
▸ RAB9A P51151 7/20 0.53
▸ MAPT P10636 6/20 0.53
▸ MAPK1 P28482 3/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.53
▸ CYP1A2 P05177 2/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ CYP2C19 P33261 2/20 0.50
▸ NPC1 O15118 5/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ LMNA P02545 4/20 0.43
▸ KDM4E B2RXH2 4/20 0.43
▸ HPGD P15428 3/20 0.43
▸ ESR1 P03372 2/20 0.41
▸ ESR2 Q92731 2/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.40
▸ XBP1 P17861 1/20 0.40
▸ GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10177473 1.00 ALDH1A1 (0.53) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL1342675 1.00 ALDH1A1 (0.53) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL10741171 0.84 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL10741173 0.84 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL2037488 0.81 ALDH1A1 (0.50) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL2037491 0.81 ALDH1A1 (0.50) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL21872319 0.81 ALDH1A1 (0.50) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL4900509 0.81 ALDH1A1 (0.50) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL3977494 0.79 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTMAPK1MEN1
SCHEMBL17412695 0.79 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700893-A Polystyrene resin material for electric insulation and preparation method thereof 深圳科瑞沃科技有限公司 2024-03-15 — — CN claimed
CN-117700893-A Polystyrene resin material for electric insulation and preparation method thereof 深圳科瑞沃科技有限公司 2024-03-15 — — CN disclosed
WO-2020159130-A1 ULTRAVIOLET ABSORBING ENCAPSULANT FOR LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING DEVICE INCLUDING SAME 코오롱인더스트리 주식회사 2020-08-06 — — WO disclosed
US-9991448-B2 Compound, luminescent material and organic light emitting device using same Shanghai Tianma AM-OLED Co., Ltd. (CN) 2018-06-05 — — US disclosed
US-9991448-B2 Compound, luminescent material and organic light emitting device using same Shanghai Tianma AM-OLED Co., Ltd. (CN) 2018-06-05 — — US disclosed
US-20170291890-A1 HETEROCYCLE SUBSTITUTED AMINO-PYRIDINE COMPOUNDS AND METHODS OF USE THEREOF Epizyme, Inc. 2017-10-12 — — US disclosed
US-20170288150-A1 COMPOUND, LUMINESCENT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE USING SAME WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) 2017-10-05 — — US disclosed
US-20170288150-A1 COMPOUND, LUMINESCENT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE USING SAME WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) 2017-10-05 — — US disclosed
US-8062429-B2 Methods of cleaning semiconductor devices at the back end of line using amidoxime compositions EKC TECHNOLOGY, INC. (US) 2011-11-22 — — US disclosed
US-20100105595-A1 COMPOSITION COMPRISING CHELATING AGENTS CONTAINING AMIDOXIME COMPOUNDS EKC TECHNOLOGY, INC. 2010-04-29 — — US disclosed
US-20090107520-A1 AMIDOXIME COMPOUNDS AS CHELATING AGENTS IN SEMICONDUCTOR PROCESSES EKC TECHNOLOGY, INC. 2009-04-30 — — US disclosed
EP-0674325-B1 Electrically insulating polymer composition and wire or cable using the same NIPPON PETROCHEMICALS CO LTD (JP) 2003-11-05 — — EP disclosed
EP-0702003-B1 Process for preparing 2-halogenpyridinaldehydes BAYER AG (DE) 1998-06-17 — — EP disclosed
US-5708180-A CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME BAYER AKTIENGESELLSCHAFT (DE) 1998-01-13 — — US disclosed
EP-0702003-A2 Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes BAYER AG (DE) 1996-03-20 — — EP disclosed
EP-0674325-A2 Electrically insulating polymer composition and wire or cable using the same Nippon Petrochemicals Co., Ltd. (JP) 1995-09-27 — — EP disclosed
US-5304619-A Containing nitrile or nitro polar groups; high voltage NIPPON PETROCHEMICALS CO., LTD. (JP) 1994-04-19 — — US disclosed
US-5254713-A 2- and 3-chloropyrroles and process for preparing the same NIHON BAYER AGROCHEM K.K. (JP) 1993-10-19 — — US disclosed
US-5210218-A 2- and 3-chloropyrroles and process for preparing the same NIHON BAYER AGROCHEM K.K. (JP) 1993-05-11 — — US disclosed
EP-0463402-A2 Ethylene polymers or copolymers having improved insulating properties, compositions, and power cables made therefrom NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170291890-A1 HETEROCYCLE SUBSTITUTED AMINO-PYRIDINE COMPOUNDS AND METHODS OF USE THEREOF HCCS, TP53, NME2 ALDH1A1 1707/4885RAB9A 1803/4885MAPT 4400/4885
US-20170288150-A1 COMPOUND, LUMINESCENT MATERIAL AND ORGANIC LIGHT EMITTING DEVICE USING SAME TRPA1, ZNF436-AS1, TRPM6 ALDH1A1 50/4885RAB9A 2430/4885MAPT 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.