Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955123 | 0.91 | HPGD (0.50) | ALDH1A1MAPT | |
| SCHEMBL134271 | 0.88 | ESR1 (0.53) | ESR1ALDH1A1 | |
| SCHEMBL10858118 | 0.83 | LMNA (0.58) | ALDH1A1MAPT | |
| SCHEMBL8234368 | 0.83 | MAPT (0.59) | ALDH1A1MAPT | |
| SCHEMBL14039496 | 0.82 | SMN1; SMN2 (0.62) | CYP19A1ESR1ALDH1A1 | |
| SCHEMBL17775077 | 0.82 | KDM4E (0.49) | ALDH1A1MAPT | |
| SCHEMBL24261132 | 0.81 | HPGD (0.44) | ALDH1A1MAPT | |
| SCHEMBL12909783 | 0.81 | LMNA (0.57) | ESR1ALDH1A1MAPT | |
| SCHEMBL3370944 | 0.81 | PTGS2 (0.56) | ALDH1A1MAPT | |
| SCHEMBL12909782 | 0.81 | L3MBTL1 (0.68) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105874062-A | Glyphosate-n-acetyltransferase (glyat) sequences and methods of use | 先锋国际良种公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2184277-B1 | ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | INST PHARM & TOXICOLOGY AMMS (CN) | 2015-07-01 | — | — | EP | disclosed |
| US-8759355-B2 | Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2014-06-24 | — | — | US | disclosed |
| US-8148373-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-20110009427-A1 | ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | INSTITUE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2011-01-13 | — | — | US | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
| US-20090099267-A1 | POLYMERS, COMPOSITIONS AND METHODS OF MAKING THE SAME | UNIVERSITY OF MASSACHUSETTS (US) | 2009-04-16 | — | — | US | disclosed |
| EP-0427480-B1 | 2-Hydroxy-3-phenoxypropylamino compounds | ICI PLC (GB) | 1994-01-12 | — | — | EP | disclosed |
| US-5187190-A | PHENOXYPROPANOLAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| EP-0427480-A1 | 2-Hydroxy-3-phenoxypropylamino compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009427-A1 | ARYL PYRIMIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | PPARD, PPARG, PPARA | LTA4H 1051/4885NR5A1 52/4885CYP19A1 488/4885 |
| US-20090099267-A1 | POLYMERS, COMPOSITIONS AND METHODS OF MAKING THE SAME | PARG, PNKP, DCXR | LTA4H 1305/4885NR5A1 4743/4885CYP19A1 2017/4885 |
| US-20090298807-A1 | Compounds | PKD1, SLC10A1, ABCB11 | LTA4H 1897/4885NR5A1 56/4885CYP19A1 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.