Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.38 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31115697 | 0.81 | APP (1.00) | APPCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL563392 | 0.81 | APP (1.00) | APPCYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL10038463 | 0.81 | APP (0.75) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| Pyrophosphoric Acid SCHEMBL12479167 | 0.81 | APP (0.80) | APPCYP1A2MEN1POLBKMT2A | |
| SCHEMBL19693028 | 0.80 | APP (0.66) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL22901077 | 0.80 | APP (0.68) | APPCYP1A2STS | |
| SCHEMBL3974521 | 0.80 | APP (0.72) | APPCYP1A2KDM4EALDH1A1POLB | |
| SCHEMBL18932158 | 0.78 | APP (0.74) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| Pyrophosphoric Acid SCHEMBL12479170 | 0.78 | APP (0.56) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| Ethoxyresorufin SCHEMBL104497 | 0.78 | APP (1.00) | APPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210018497-A1 | BRET SENSOR MOLECULES FOR DETECTING HYDROLASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2021-01-21 | — | — | US | disclosed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
| WO-2015144282-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2015-10-01 | — | — | WO | disclosed |
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| EP-1427852-B1 | SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1421213-B1 | LABELED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| US-7560254-B2 | Allele specific primer extension | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560254-B2 | Allele specific primer extension | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2009-07-14 | — | — | US | disclosed |
| WO-2008087031-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
| US-7393640-B2 | Terminal-phosphate-labeled nucleotides with new linkers | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-07-01 | — | — | US | disclosed |
| US-7393640-B2 | Terminal-phosphate-labeled nucleotides with new linkers | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-07-01 | — | — | US | disclosed |
| US-7244566-B2 | Detecting one or more biopolymers using terminal phosphate labeled nucleotides; labels employed are enzyme-activatable and include chemiluminescent, fluorescent, electrochemical and chromophoric moieties | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244566-B2 | Detecting one or more biopolymers using terminal phosphate labeled nucleotides; labels employed are enzyme-activatable and include chemiluminescent, fluorescent, electrochemical and chromophoric moieties | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7223541-B2 | Terminal-phosphate-labeled nucleotides and methods of use | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223541-B2 | Terminal-phosphate-labeled nucleotides and methods of use | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112948-A1 | Inorganic-organic hybrid compound | SLCO4C1, SLCO2A1, SLCO1A2 | APP 1150/4885CYP1A2 1592/4885STS 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.