Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496681 | 0.95 | TDP1 (0.44) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL13310832 | 0.91 | LMNA (0.41) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL13428187 | 0.91 | LMNA (0.41) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL14496675 | 0.86 | LMNA (0.37) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL13538730 | 0.86 | LMNA (0.45) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL13883752 | 0.86 | CA2 (0.40) | TDP1LMNAALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL14455222 | 0.81 | LMNA (0.41) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL7112122 | 0.80 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL6881757 | 0.80 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL7112124 | 0.80 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |